Neonatal Resuscitation Algorithm: A Modern, Step-by-Step Guide
Neonatal Resuscitation • Education

Neonatal Resuscitation Algorithm — The First 10 Minutes

A modern walkthrough of the newborn resuscitation flow—antenatal prep, first-minute questions, warm/dry/clear airway, when to start PPV vs CPAP, heart-rate checkpoints (100 and 60), ETT/laryngeal mask, compressions, epinephrine, and targeted SpO₂.

Educational only—follow your institution’s NRP protocol and a licensed clinician’s direction.

In this guide:

Preparation before birth

Assign roles (airway, compressor, meds, recorder) and agree on communication script before delivery.

The first minute after birth

Three key questions

  • Term gestation?
  • Good tone?
  • Breathing or crying?

If all yes → infant remains with parent for routine care: warm, maintain temperature, position airway, clear secretions if needed, dry, and continue evaluation.

Ventilation pathway

Labored breathing or persistent cyanosis?

  • Position & clear airway, monitor SpO₂
  • Supplemental oxygen as needed; consider CPAP

Heart-rate checkpoints

After PPV — is HR < 100?

  • Check chest movement; perform ventilation corrective steps (MR SOPA)
  • Consider ETT or laryngeal mask if needed

Is HR < 60?

  • Intubate (if not already), begin chest compressions
  • Coordinate with PPV using 100% O₂; add ECG monitor
  • Consider emergency UVC

If HR remains < 60

Post-resuscitation care and team debriefing improve systems and outcomes—schedule them deliberately.

Targeted preductal SpO₂ after birth

Time after birth SpO₂ target Referral
1 min60%–65%SpO₂ Targets
2 min65%–70%
3 min70%–75%
4 min75%–80%
5 min80%–85%
10 min85%–95%

Cited Keywords & Referral Links

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Bottom line

In the delivery room, think warm-position-clear-dry-stimulate, then ventilate early if apnea/gasping or HR < 100. If HR drops below 60 despite effective ventilation, intubate, coordinate compressions with PPV and 100% oxygen, establish UVC, and give epinephrine. Target SpO₂ ranges and debrief after every event.

This guide is for education and does not replace clinical judgment or local NRP protocols.

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