Cardiac Arrest in Pregnancy: In-Hospital ACLS Algorithm (Modern Guide)
Maternal Resuscitation • Education

Cardiac Arrest in Pregnancy: In-Hospital ACLS Algorithm

A fast, modern overview of the maternal cardiac arrest pathway—BLS/ACLS continuation, team assembly, airway and oxygenation, obstetric actions, and when to perform perimortem cesarean delivery.

Educational only—follow institutional protocols and a licensed clinician’s direction.

In this guide:

Continue High-Quality BLS/ACLS

Assemble a Maternal Cardiac Arrest Team

Coordinate with obstetrics, neonatal, anesthesia, critical care, and cardiology teams.

  • Prioritize continuous high-quality CPR and left uterine displacement
  • Goal: optimize maternal circulation and improve fetal outcomes

Consider the Etiology of Cardiac Arrest

CategoryExamples / NotesLearn more
Anesthetic complicationsAirway events, local anesthetic systemic toxicityAnesthesia
BleedingPostpartum hemorrhage, DICObstetric hemorrhage
CardiovascularMI, cardiomyopathy, aortic dissectionCardiovascular
DrugsToxicity, overdoseToxicology
EmbolicAmniotic fluid embolism, PEPulmonary Embolism
H’s & T’sStandard reversible causes (hypoxia, hypovolemia, tension pneumothorax, etc.)ACLS review
HypertensionSevere preeclampsia/eclampsia, intracranial hemorrhagePreeclampsia

Maternal Interventions

Obstetric Interventions

Perimortem Cesarean Delivery (PMCD)

If ROSC is not achieved within ~5 minutes, proceed with PMCD when resources/skills permit. The goal is to relieve aortocaval compression and improve maternal perfusion; neonatal team should be ready to receive the newborn.

Advanced Airway in Pregnancy

  • Anticipate difficult airway; involve the most experienced provider
  • Consider supraglottic airway if intubation fails
  • Confirm placement (capnography) and monitor
  • Once advanced airway is in place, give 1 breath every 6 seconds (10 breaths/min) while continuing compressions
  • Avoid hyperventilation; target visible chest rise and adequate oxygenation

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Bottom line

During maternal cardiac arrest, prioritize high-quality CPR, prompt defibrillation when indicated, left uterine displacement, and parallel maternal/obstetric interventions. If there’s no ROSC within ~5 minutes, proceed to PMCD while the neonatal team prepares for delivery.

This guide is for education only and does not replace clinical judgment or local protocols.

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