Maternal Resuscitation • Education

Cardiac Arrest in Pregnancy: In-Hospital ACLS Algorithm

A fast, modern overview of the maternal cardiac arrest pathway—BLS/ACLS continuation, team assembly, airway and oxygenation, obstetric actions, and when to perform perimortem cesarean delivery.

Educational only—follow institutional protocols and a licensed clinician’s direction.

In this guide:

Continue High-Quality BLS/ACLS

  • Immediate high-quality CPR; minimize pauses; ensure effective compressions
  • Defibrillation when indicated
  • Other ACLS interventions (e.g., epinephrine) per rhythm

Assemble a Maternal Cardiac Arrest Team

Coordinate with obstetrics, neonatal, anesthesia, critical care, and cardiology teams.

  • Prioritize continuous high-quality CPR and left uterine displacement
  • Goal: optimize maternal circulation and improve fetal outcomes

Consider the Etiology of Cardiac Arrest

Category Examples / Notes Learn more
Anesthetic complications Airway events, local anesthetic systemic toxicity Anesthesia
Bleeding Postpartum hemorrhage, DIC Obstetric hemorrhage
Cardiovascular MI, cardiomyopathy, aortic dissection Cardiovascular
Drugs Toxicity, overdose Toxicology
Embolic Amniotic fluid embolism, PE Pulmonary Embolism
H’s & T’s Standard reversible causes (hypoxia, hypovolemia, tension pneumothorax, etc.) ACLS review
Hypertension Severe preeclampsia/eclampsia, intracranial hemorrhage Preeclampsia

Maternal Interventions

Obstetric Interventions

Perimortem Cesarean Delivery (PMCD)

If ROSC is not achieved within ~5 minutes, proceed with PMCD when resources/skills permit. The goal is to relieve aortocaval compression and improve maternal perfusion; neonatal team should be ready to receive the newborn.

Advanced Airway in Pregnancy

  • Anticipate difficult airway; involve the most experienced provider
  • Consider supraglottic airway if intubation fails
  • Confirm placement (capnography) and monitor
  • Once advanced airway is in place, give 1 breath every 6 seconds (10 breaths/min) while continuing compressions
  • Avoid hyperventilation; target visible chest rise and adequate oxygenation

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Bottom line

During maternal cardiac arrest, prioritize high-quality CPR, prompt defibrillation when indicated, left uterine displacement, and parallel maternal/obstetric interventions. If there’s no ROSC within ~5 minutes, proceed to PMCD while the neonatal team prepares for delivery.

This guide is for education only and does not replace clinical judgment or local protocols.

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